Language
Search
News
- Bruker Hosts 10th Annual International Nanoscience Conference
- Bruker Acquires Hecus MICROcaliX(R) Product Line to Expand Product Portfolio for Small Angle X-ray Scattering (SAXS)
- Bruker Announces $1.3 Million Contract with ThyssenKrupp Stainless USA
- Lab Report SC-XRD 46 - Higher Dimensional Crystallography
- Lab Report XRF 103 - S2 RANGER with XFlash LE and GEO-QUANT M
Upcoming Events
- The Benefits of TXRF for Education and University Research
Mar 07, Webinar - Pittcon 2012
Mar 11-15, Orlando, Florida, USA - SEMICON China 2012
Mar 20-22, Shanghai, China - ARAB LAB 2012
Mar 26-29, Dubai, UAE - 2012 NUANCE-Bruker International Symposium
Apr 05, Evanston, IL, USA - ANALYTICA 2012
Apr 17-20, Munich, Germany
Life Sciences
- Life Science
Life Science research continues to be of growing importance both in academia and industry. At the same time it has become an increasingly competitive area, particularly with respect to research and development as well as production control. Bruker AXS offers a variety of solutions supporting your efforts in this field:
Structural Biology
The biological functions of macromolecules are governed by their three-dimensional structures. Whether you are studying proteins, nucleic acids, membrane bound complexes or viruses, a detailed knowledge of the structure (structure gallery) is the key to a precise understanding of the function and mechanism of action of these bio-molecules. X-ray crystallography is the most productive method for obtaining accurate structural models of macromolecules. Small angle X-ray scattering (SAXS) is fast becoming the tool of choice to studying the structure and interactions of biological macromolecules.
- Structural Biology
Protein Folding and Function
Information about the size, shape, and conformational changes of biological materials in solution can be easily obtained by Small Angle X-ray Scattering (SAXS) experiments - for instance with the NANOSTAR. Combining SAXS results with high resolution structures enables detailed characterization of the structures of large assemblies, and conformational changes associated with protein folding or function.
Clinical Testing
In clinical laboratories blood samples are routinely tested for essential elements as well as toxic elements. Monitoring of the application of chemotherapeutical drugs require an accurate method for long-term examination using small amounts of patients’ blood.
Biological Trace Element Analysis
Complementary information on the function of metals in bio-molecules (Metallomics) is easily revealed by the micro-analytical capabilities of Total Reflection X-ray Fluorescence (TXRF) spectroscopy. Stoichiometric determination of the metal content of proteins can provie key insight into enzyme function and regulation.
- Pharmaceuticals
Pharmaceutical Research and Production Control
The entire pharmaceutical value chain, be it drug discovery, drug development or production takes benefit from X-ray fluorescence and diffraction methods. These methods are successfully used in discovery, screening, optimization, production, and authenticity tests of drugs.
